Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31081585 | 0.69 | TSHR (0.38) | TSHR | |
| SCHEMBL3819026 | 0.67 | TSHR (0.33) | TSHR | |
| SCHEMBL15141 | 0.67 | TSHR (0.33) | TSHR | |
| Methyl Alcohol SCHEMBL28674412 | 0.67 | — | — | |
| Methyl Alcohol SCHEMBL28536398 | 0.67 | TSHR (0.35) | TSHR | |
| Hydrochloric Acid SCHEMBL11650945 | 0.67 | TSHR (0.35) | TSHR | |
| Methyl Alcohol SCHEMBL9490486 | 0.67 | TSHR (0.35) | TSHR | |
| Methyl Alcohol SCHEMBL28412835 | 0.67 | TSHR (0.35) | TSHR | |
| SCHEMBL212871 | 0.65 | — | — | |
| SCHEMBL728051 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619865-A | Preparation method of diisoisothiocyanate | 四川国和新材料有限公司 | 2024-09-10 | — | — | CN | claimed |
| US-5374744-A | Sex pheronome of Japanese beetle, cupreous chafers; oxidation, reduction, cleavage, cyclization, alkynylation, hydrolysis | JAPAN TOBACCO INC. (JP) | 1994-12-20 | — | — | US | claimed |
| CN-118619865-B | Preparation method of diisoisothiocyanate | 四川国和新材料有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-118619865-A | Preparation method of diisoisothiocyanate | 四川国和新材料有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-113072551-B | Nitrogen-containing biphenyl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-111542939-A | Organic semiconductor element, organic semiconductor composition, organic semiconductor film, method for producing organic semiconductor film, and polymer for use in these | 富士胶片株式会社 | 2020-08-14 | — | — | CN | disclosed |
| CN-106478496-A | Dihydropyridine sulfonamide and dihydropyridine sulphamide as mek inhibitor | 阿迪生物科学公司 | 2017-03-08 | — | — | CN | disclosed |
| EP-2411366-B1 | DIHYDROPYRIDIN SULFONAMIDES AND DIHYDROPYRIDIN SULFAMIDES AS MEK INHIBITORS | ARDEA BIOSCIENCES INC (US) | 2015-05-20 | — | — | EP | disclosed |
| US-8993630-B2 | Substituted sulphonamido phenoxybenzamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-8962606-B2 | Substituted benzosulphonamides | BAYER INTELLECTUAL PROPERTY GMBH (US) | 2015-02-24 | — | — | US | disclosed |
| US-8673919-B2 | Dihydropyridin sulfonamides and dihydropyridin sulfamides as MEK inhibitors | ARDEA BIOSCIENCES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| WO-2008138639-A1 | SUBSTITUTED PHENYLAMINO-BENZENE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH MITOGEN EXTRACELLULAR KINASE ACTIVITY | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-11-20 | — | — | WO | disclosed |
| EP-1414809-B1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER CORP (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |
| WO-2003030909-A1 | 2- AND 4-AMINOPYRIMIDINES N-SUBSTTITUDED BY A BICYCLIC RING FOR USE AS KINASE INHIBITORS IN THE TREATMENT OF CANCER | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-17 | — | — | WO | disclosed |
| CN-1245773-A | Process for producing chlorine | SUMITOMO CHEMICAL CO (JP) | 2000-03-01 | — | — | CN | disclosed |
| EP-0528044-B1 | Process for producing 4-substituted gamma- lactone, and the so produced novel substances. | JAPAN TOBACCO INC (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5374744-A | Sex pheronome of Japanese beetle, cupreous chafers; oxidation, reduction, cleavage, cyclization, alkynylation, hydrolysis | JAPAN TOBACCO INC. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0528044-A1 | PROCESS FOR PRODUCING 4-SUBSTITUTED $g(g)-LACTONE, AND NOVEL SUBSTANCE | JAPAN TOBACCO INC. (JP) | 1993-02-24 | — | — | EP | disclosed |
| US-4304907-A | Bicyclo lactone intermediates for prostaglandin analogs | THE UPJOHN COMPANY (US) | 1981-12-08 | — | — | US | disclosed |