SCHEMBL4868547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6102556	0.92	KDR (0.67)	KDREPHA2EPHB4FLT1EGFR
	SCHEMBL9910688	0.90	EGFR (0.69)	KDREPHA2EPHB4FLT1EGFR
	SCHEMBL6103476	0.88	KDR (0.64)	KDREPHA2EPHB4FLT1EGFR
	SCHEMBL9910674	0.87	EGFR (0.71)	KDREPHA2EPHB4FLT1EGFR
	SCHEMBL906880	0.86	EPHA2 (1.00)	KDREPHA2EPHB4FLT1EGFR
	SCHEMBL4867054	0.86	KDR (0.65)	KDREPHA2EPHB4FLT1EGFR
	SCHEMBL9910672	0.86	EGFR (0.86)	KDREPHA2EPHB4EGFRGAK
	SCHEMBL4577785	0.85	EGFR (0.76)	KDREPHA2EPHB4FLT1EGFR
	SCHEMBL2255348	0.84	EGFR (0.69)	KDREPHA2EPHB4EGFRGAK
	SCHEMBL5125818	0.84	EGFR (0.60)	KDREPHA2EPHB4FLT1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.