Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31382687 | 1.00 | SCN9A (0.39) | SCN9ASCN2ASCN3ASCN10AMAP4K4 | |
| SCHEMBL1013695 | 0.82 | PIK3CB (0.47) | MAP4K4IDO1PIK3CBKDM4E | |
| SCHEMBL1319218 | 0.82 | CYP3A4 (0.50) | MAP4K4SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL11555230 | 0.82 | MAP4K4 (0.40) | SCN9ASCN2ASCN3ASCN10AMAP4K4 | |
| Hydrochloric Acid SCHEMBL11549048 | 0.81 | CYP3A4 (0.48) | MAP4K4SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL915037 | 0.81 | CYP3A4 (0.48) | MAP4K4SMN1; SMN2RAB9AMAPTKDM4E | |
| SCHEMBL29733564 | 0.80 | ABL1 (0.51) | MAPTKDM4EHPGDIKBKETBK1 | |
| SCHEMBL914850 | 0.80 | ABL1 (0.51) | MAPTKDM4EHPGDIKBKETBK1 | |
| SCHEMBL15081394 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2PIK3CBKDM4EIKBKETBK1 | |
| SCHEMBL4971916 | 0.80 | MAPK1 (0.40) | MAPK1PTK2SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER INC | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PDE5A, PDE3B, PDE12 | SCN9A 799/4885SCN2A 1927/4885SCN3A 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.