Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866392 | 0.89 | POLB (0.36) | POLBSYKLMNAKDM4EFASN | |
| SCHEMBL4867317 | 0.88 | HTT (0.40) | POLBSYKLMNAKDM4EFASN | |
| SCHEMBL6241915 | 0.87 | GAA (0.39) | SYKGAA | |
| SCHEMBL4872289 | 0.87 | GAA (0.39) | SYKGAA | |
| SCHEMBL4864188 | 0.85 | SYK (0.36) | POLBSYKLMNAKDM4EFASN | |
| SCHEMBL4873664 | 0.84 | KDM4E (0.36) | POLBSYKLMNAKDM4EFASN | |
| SCHEMBL4870898 | 0.83 | POLB (0.36) | POLBSYKLMNAKDM4EFASN | |
| SCHEMBL4870528 | 0.76 | — | — | |
| SCHEMBL4864629 | 0.76 | GAA (0.41) | SYKGAA | |
| SCHEMBL4867247 | 0.75 | SYK (0.38) | SYKALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332485-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2008-02-19 | — | — | US | disclosed |