Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871535 | 0.91 | MEN1 (0.46) | RARBS1PR1SPHK2FAAHS1PR4 | |
| SCHEMBL4862292 | 0.89 | RARB (0.38) | RARBS1PR1ALDH1A1CYP3A4 | |
| SCHEMBL4862352 | 0.89 | RARB (0.38) | RARBS1PR1ALDH1A1CYP3A4 | |
| SCHEMBL4870576 | 0.88 | RARB (0.39) | RARBS1PR1ALDH1A1CYP3A4 | |
| SCHEMBL4871834 | 0.88 | RARB (0.39) | RARBS1PR1ALDH1A1CYP3A4 | |
| SCHEMBL9495429 | 0.87 | RARB (0.51) | RARBS1PR1FAAHMEN1USP2 | |
| SCHEMBL17897418 | 0.87 | RARB (0.51) | RARBS1PR1FAAHMEN1USP2 | |
| SCHEMBL9475235 | 0.87 | RARB (0.51) | RARBS1PR1FAAHMEN1USP2 | |
| SCHEMBL9493510 | 0.87 | RARB (0.51) | RARBS1PR1FAAHMEN1USP2 | |
| SCHEMBL9486838 | 0.87 | RARB (0.51) | RARBS1PR1FAAHMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351452-B2 | Liquid crystalline compounds containing a biphenyl core | QINETIQ LIMITED (GB) | 2008-04-01 | — | — | US | disclosed |
| US-20050001200-A1 | Liquid crystalline compounds containing a biphenyl core | QINETIQ LIMITED (GB) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050001200-A1 | Liquid crystalline compounds containing a biphenyl core | YBX1, AFF1, AFF2 | RARB 1075/4885S1PR1 3203/4885SPHK2 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.