⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135521 | 0.78 | — | — | |
| SCHEMBL3421317 | 0.78 | — | — | |
| SCHEMBL3420657 | 0.78 | — | — | |
| SCHEMBL8172367 | 0.73 | — | — | |
| SCHEMBL487128 | 0.67 | — | — | |
| SCHEMBL7732139 | 0.67 | — | — | |
| SCHEMBL9021365 | 0.67 | — | — | |
| SCHEMBL7050529 | 0.67 | — | — | |
| SCHEMBL23612 | 0.67 | — | — | |
| SCHEMBL4204596 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344404-A1 | PDK4 INHIBITOR AND USE THEREOF | THE KITASATO INSTITUTE (JP) | 2015-12-03 | — | — | US | disclosed |
| EP-2939668-A1 | PDK4 INHIBITOR AND USE THEREOF | The Kitasato Institute (JP) | 2015-11-04 | — | — | EP | disclosed |
| CN-102391203-A | Intermediate of 6-substituted-1-methyl-1-h-benzimidazole derivative and method for producing same | SANKYO CO | 2012-03-28 | — | — | CN | disclosed |
| US-8106079-B2 | Intermediate of 6-substituted-1-methyl-1-H-benzimidazole derivative and method for producing same | SANKYO COMPANY, LIMITED (JP) | 2012-01-31 | — | — | US | disclosed |
| CN-101068770-B | Process for producing 6-substituted-1-methyl-1-H-benzimidazole derivative and synthetic intermediate therefor | SANKYO CO | 2012-01-04 | — | — | CN | disclosed |
| US-7816552-B2 | Intermediate of 6-substituted 1-methyl-1-H-benzimidazole derivative and method for producing same | SANKYO COMPANY, LIMITED (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20100234612-A1 | Intermediate of 6-substituted-1-methyl-1-H-benzimidazole derivative and method for producing same | SANKYO COMPANY, LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20090023929-A1 | Intermediate of 6-Substituted 1-Methyl-1-H-Benzimidazole Derivative and Method for Producing Same | SANKYO COMPANY, LIMITED (JP) | 2009-01-22 | — | — | US | disclosed |
| CN-101068770-A | Process for producing 6-substituted-1-methyl-1-H-benzimidazole derivative and synthetic intermediate therefor | SANKYO CO (JP) | 2007-11-07 | — | — | CN | disclosed |
| EP-1798216-A1 | INTERMEDIATE OF 6-SUBSTITUTED-1-METHYL-1-H-BENZIMIDAZOLE DERIVATIVE AND METHOD FOR PRODUCING SAME | Sankyo Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| US-4820821-A | ANTIDEPRESSANTS, ANTIHYPOTONIC AGENTS, ANTIPARKINSON DRUGS | BASF AKTIENGESELLSCHAFT (DE) | 1989-04-11 | — | — | US | disclosed |
| EP-0078989-B1 | PYRIDAZINONE IMINES AND THEIR PHYSIOLOGICALLY TOLERABLE ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING THOSE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1985-05-08 | — | — | EP | disclosed |