Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864724 | 0.97 | TLR8 (0.39) | TLR7TLR8PIK3CALMNABRAF | |
| SCHEMBL4793675 | 0.86 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL4790933 | 0.85 | TLR7 (0.41) | TLR7TLR8ALOX5APFEN1 | |
| SCHEMBL4792552 | 0.83 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL4882511 | 0.83 | TLR7 (0.48) | TLR7TLR8 | |
| SCHEMBL4877651 | 0.83 | TLR7 (0.41) | TLR7TLR8 | |
| SCHEMBL4875546 | 0.82 | EDNRA (0.37) | PIK3CABRAFPI4KAPIK3CG | |
| SCHEMBL4790566 | 0.81 | TLR7 (0.36) | TLR7TLR8PIK3CAALOX5APFEN1 | |
| SCHEMBL4880838 | 0.81 | TLR7 (0.35) | TLR7TLR8PIK3CAPIK3CG | |
| SCHEMBL5343016 | 0.81 | TLR7 (0.36) | TLR7TLR8PIK3CAALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |