SCHEMBL4873932

SCHEMBL4873932

[AsH2]c1ccc(Cn2cncn2)cc1

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 17/20 0.67
HDAC1 Q13547 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
UGT1A4 P22310 1/20 0.43
PDE4D Q08499 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17159812 0.90 CYP19A1 (0.80) CYP19A1HDAC1HDAC6UGT1A4PDE4D
SCHEMBL3460891 0.85 CYP19A1 (0.67) CYP19A1HDAC1HDAC6UGT1A4PDE4D
SCHEMBL15688800 0.84 CYP19A1 (0.71) CYP19A1HDAC1HDAC6
SCHEMBL11354103 0.82 CYP19A1 (0.69) CYP19A1HDAC1HDAC6
SCHEMBL3235365 0.82 CYP19A1 (0.69) CYP19A1HDAC1HDAC6
Hydrochloric Acid SCHEMBL11358575 0.81 CYP19A1 (0.67) CYP19A1HDAC1HDAC6
SCHEMBL307542 0.81 CYP19A1 (0.67) CYP19A1HDAC1HDAC6
SCHEMBL3318872 0.81 CYP19A1 (0.67) CYP19A1HDAC1HDAC6UGT1A4PDE4D
SCHEMBL306232 0.81 CYP19A1 (0.67) CYP19A1HDAC1HDAC6UGT1A4PDE4D
SCHEMBL3319920 0.81 CYP19A1 (0.67) CYP19A1HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951713-A1 PROCESS FOR THE LARGE SCALE PRODUCTION OF RIZATRIPTAN BENZOATE Matrix Laboratories Ltd (IN) 2008-08-06 EP claimed
WO-2007054979-A1 PROCESS FOR THE LARGE SCALE PRODUCTION OF RIZATRIPTAN BENZOATE MATRIX LABORATORIES LTD (IN) 2007-05-18 WO claimed