Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | AGXT | P21549 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222385 | 0.86 | TAAR1 (0.58) | TAAR1IDO1AGXTAOC3ALDH1A1 | |
| SCHEMBL22458119 | 0.83 | TAAR1 (0.54) | TAAR1IDO1AGXTAOC3ALDH1A1 | |
| SCHEMBL24177286 | 0.83 | TAAR1 (0.54) | TAAR1IDO1AGXTAOC3ALDH1A1 | |
| SCHEMBL73635 | 0.82 | TAAR1 (0.56) | TAAR1IDO1AGXTAOC3ALDH1A1 | |
| SCHEMBL29557981 | 0.79 | TAAR1 (0.59) | TAAR1IDO1AGXTAOC3ALDH1A1 | |
| SCHEMBL20746169 | 0.79 | TAAR1 (0.59) | TAAR1IDO1AGXTAOC3ALDH1A1 | |
| SCHEMBL809219 | 0.79 | TAAR1 (0.53) | TAAR1IDO1AGXTAOC3ALDH1A1 | |
| SCHEMBL8325279 | 0.79 | TAAR1 (0.53) | TAAR1IDO1AGXTAOC3MAOB | |
| SCHEMBL30183964 | 0.79 | TAAR1 (0.53) | TAAR1IDO1AGXTAOC3MAOB | |
| SCHEMBL2036352 | 0.78 | BLM (0.55) | TAAR1IDO1AGXTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7436465-B2 | Electrooptical device region and manufacturing method thereof, electrooptical device and electronic equipment | SEIKO EPSON CORPORATION (JP) | 2008-10-14 | — | — | US | disclosed |
| US-20050162366-A1 | Electrooptical device region and manufacturing method thereof, electrooptical device and electronic equipment | SEIKO EPSON CORPORATION (JP) | 2005-07-28 | — | — | US | disclosed |
| US-4581172-A | Substituted pyrimido[6,1-a]isoquinolin-4-ones,pyrimido[6,1-a]benzozepin-4-ones and pyrimido[6,1-a]benzodiazepin-4-ones useful for prevention of thromboses and treating hypertension | HOFFMANN-LA ROCHE INC. (US) | 1986-04-08 | — | — | US | disclosed |