⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456720 | 1.00 | — | — | |
| SCHEMBL8433309 | 1.00 | — | — | |
| SCHEMBL487464 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28237384 | 0.97 | — | — | |
| Methane SCHEMBL2578408 | 0.97 | — | — | |
| SCHEMBL18460252 | 0.92 | — | — | |
| SCHEMBL99053 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL28238151 | 0.89 | — | — | |
| SCHEMBL20144349 | 0.89 | — | — | |
| Methane SCHEMBL5743567 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106057-B2 | Dihydroxyphenyl isoindolylmethanones | ASTEX THERAPEUTICS, LTD. (GB) | 2012-01-31 | — | — | US | disclosed |
| US-20100286167-A1 | DIHYDROXYPHENYL ISOINDOLYLMETHANONES | ASTEX THERAPEUTICS LTD. (GB) | 2010-11-11 | — | — | US | disclosed |
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010004347-A1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |
| EP-0255149-A1 | Pyrrolidin-2-one derivatives having nootropic activity | GIBIPHARMA S.p.A. (IT) | 1988-02-03 | — | — | EP | disclosed |
| US-4110380-A | Asymmetric synthesis of organic compounds | HOFFMANN-LA ROCHE INC. (US) | 1978-08-29 | — | — | US | disclosed |
| US-4105696-A | Asymmetric synthesis of organic compounds | HOFFMANN-LA ROCHE INC. (US) | 1978-08-08 | — | — | US | disclosed |