SCHEMBL4875153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4884354	0.89	KDR (0.50)	MEN1NPC1LMNAMAPTMAPK1
	SCHEMBL14024756	0.88	AURKA (0.53)	MEN1NPC1LMNAMAPTMAPK1
	SCHEMBL14024667	0.87	KDR (0.48)	MEN1NPC1LMNAMAPTMAPK1
	SCHEMBL14024591	0.86	EIF2AK2 (0.52)	MEN1NPC1LMNAMAPTMAPK1
	SCHEMBL4884243	0.85	KDR (0.46)	MEN1NPC1LMNAMAPTMAPK1
	SCHEMBL15494815	0.85	KDR (0.49)	MEN1NPC1LMNAMAPTMAPK1
	SCHEMBL14024657	0.84	KDR (0.53)	MEN1NPC1LMNAMAPTMAPK1
	SCHEMBL14024579	0.84	KDR (0.47)	KDRSYKCDK4CDK2AURKA
	SCHEMBL14024583	0.83	EGFR (0.63)	KDRIGF1RCDK4CDK2EGFR
	SCHEMBL4879994	0.83	CDK2 (0.53)	KDREIF2AK2SYKCDK4CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.