Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4792366 | 0.90 | HPGD (0.39) | TLR7TLR8SMN1; SMN2HPGDLMNA | |
| SCHEMBL4792078 | 0.89 | HPGD (0.39) | TLR7TLR8SMN1; SMN2HPGDLMNA | |
| SCHEMBL4794750 | 0.89 | HPGD (0.39) | TLR7TLR8SMN1; SMN2HPGDLMNA | |
| SCHEMBL4792944 | 0.88 | HPGD (0.40) | TLR7TLR8SMN1; SMN2HPGDLMNA | |
| SCHEMBL4791339 | 0.88 | TLR7 (0.36) | TLR7TLR8SMN1; SMN2HPGDLMNA | |
| SCHEMBL4790904 | 0.87 | TLR7 (0.36) | TLR7TLR8SMN1; SMN2HPGDLMNA | |
| SCHEMBL4794694 | 0.87 | TLR7 (0.38) | TLR7TLR8SMN1; SMN2HPGDLMNA | |
| SCHEMBL4792722 | 0.86 | TLR7 (0.37) | TLR7TLR8SMN1; SMN2HPGD | |
| SCHEMBL4792040 | 0.85 | TLR7 (0.37) | TLR7TLR8SMN1; SMN2HPGD | |
| SCHEMBL4792859 | 0.85 | TLR7 (0.36) | TLR7TLR8SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |