Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.90 |
| ▸ | CA4 | P22748 | 4/20 | 0.61 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL25236528 | 1.00 | CA1 (0.90) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL7567062 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL22077624 | 0.95 | — | — | |
| Acetic Acid SCHEMBL1332530 | 0.95 | — | — | |
| Acetic Acid SCHEMBL1331799 | 0.95 | — | — | |
| Acetic Acid SCHEMBL4818925 | 0.95 | CA1 (0.89) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1332333 | 0.95 | — | — | |
| Acetic Acid SCHEMBL153505 | 0.95 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1964006 | 0.95 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL2289 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459067-B2 | Semi-permanent reference electrode | SOUTHWEST RESEARCH INSTITUTE (US) | 2008-12-02 | — | — | US | claimed |
| US-20080128294-A1 | working electrode; voltmeter to measure potential difference between working and reference electrode; power supply; electrode internal chamber; saturated salt solution with constant pH from hygroscopic solid salt; oxidized metal wire relatively stable reference point, low rate of corrosion; pipelines | SOUTHWEST RESEARCH INSTITUTE | 2008-06-05 | — | — | US | claimed |
| WO-2004097906-A2 | SEMI-PERMANENT REFERENCE ELECTRODE | SOUTHWEST RESEARCH INSTITUTE (US) | 2004-11-11 | — | — | WO | claimed |
| CN-117986927-A | Ink compositions and films with narrow band emissive phosphor materials | 通用电气公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-112852199-B | Preparation method of cement-based steel structure protective coating | 开封大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-112852199-A | Preparation method of cement-based steel structure protective coating | 开封大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-103173460-A | Allogeneic tumor therapeutic agent | MOLOGEN AG | 2013-06-26 | — | — | CN | disclosed |
| US-7459067-B2 | Semi-permanent reference electrode | SOUTHWEST RESEARCH INSTITUTE (US) | 2008-12-02 | — | — | US | disclosed |
| US-20080128294-A1 | working electrode; voltmeter to measure potential difference between working and reference electrode; power supply; electrode internal chamber; saturated salt solution with constant pH from hygroscopic solid salt; oxidized metal wire relatively stable reference point, low rate of corrosion; pipelines | SOUTHWEST RESEARCH INSTITUTE | 2008-06-05 | — | — | US | disclosed |
| JP-2006008535-A | MAGNESIUM-SODIUM ACETATE DOUBLE SALT AND ANTIFREEZING AGENT | YONEYAMA KAGAKU KOGYO KK | 2006-01-12 | — | — | JP | disclosed |
| CN-1712487-A | Antifreezing agent | YONEYAMA KAGAKU KOGYO KK (JP) | 2005-12-28 | — | — | CN | disclosed |
| WO-2004097906-A2 | SEMI-PERMANENT REFERENCE ELECTRODE | SOUTHWEST RESEARCH INSTITUTE (US) | 2004-11-11 | — | — | WO | disclosed |