Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12022414 | 1.00 | MEN1 (0.48) | MEN1KMT2AMAPTATMANPEP | |
| SCHEMBL2550467 | 0.97 | MEN1 (0.44) | MEN1KMT2AMAPTATMANPEP | |
| SCHEMBL11066505 | 0.85 | MEN1 (0.40) | MEN1KMT2AMAPTATMANPEP | |
| SCHEMBL9695349 | 0.81 | — | — | |
| SCHEMBL27565285 | 0.78 | CYP3A4 (0.39) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL22663439 | 0.78 | KDM4E (0.34) | MEN1KMT2AALDH1A1ADRA2C | |
| SCHEMBL20368812 | 0.76 | HRH3 (0.40) | MEN1KMT2AMAPTHRH3SIGMAR1 | |
| SCHEMBL23869469 | 0.76 | CYP3A4 (0.38) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL425336 | 0.76 | MEN1 (0.55) | MEN1KMT2AMAPTATMANPEP | |
| SCHEMBL426509 | 0.76 | MEN1 (0.55) | MEN1KMT2AMAPTATMANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005002522-A2 | COMPOSITIONS AND METHODS FOR TREATING TISSUE ISCHEMIA | CARITAS ST. ELIZABETH'S MEDICAL CENTER OF BOSTON, INC. (US) | 2005-01-13 | — | — | WO | claimed |
| EP-1991221-A2 | METHODS FOR INCREASING BLOOD FLOW AND/OR PROMOTING TISSUE REGENERATION | Genzyme Corporation (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007106063-A2 | METHODS FOR INCREASING BLOOD FLOW AND/OR PROMOTING TISSUE REGENERATION | GENZYME CORPORATION (US) | 2007-09-20 | — | — | WO | disclosed |