Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878421 | 0.90 | SOAT1 (0.50) | SOAT1DRD4DRD2 | |
| SCHEMBL4876634 | 0.85 | SOAT1 (0.52) | SOAT1DRD4DRD2KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL4880947 | 0.85 | SOAT1 (0.51) | SOAT1DRD4DRD2KMT2AMEN1 | |
| SCHEMBL4881102 | 0.84 | SOAT1 (0.51) | SOAT1DRD4DRD2KMT2A | |
| SCHEMBL4880002 | 0.83 | SOAT1 (0.50) | SOAT1DRD4DRD2KMT2AHTR1A | |
| SCHEMBL4872157 | 0.82 | KMT2A (0.51) | SOAT1KMT2AHTR1A | |
| SCHEMBL4881317 | 0.81 | SOAT1 (0.49) | SOAT1DRD4DRD2KMT2AMEN1 | |
| SCHEMBL14520343 | 0.81 | SOAT1 (0.57) | SOAT1DRD4DRD2 | |
| SCHEMBL4878061 | 0.80 | SOAT1 (0.58) | SOAT1DRD4DRD2KMT2AMEN1 | |
| SCHEMBL14520340 | 0.79 | SOAT1 (0.55) | SOAT1DRD4DRD2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | SOAT1 502/4885DRD4 191/4885DRD2 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.