Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876953 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNANPY5RCYP2C19HRH3 | |
| SCHEMBL4885388 | 0.79 | NPY5R (0.58) | SMN1; SMN2LMNANPY5RCYP2C19 | |
| SCHEMBL4882812 | 0.75 | HRH3 (0.48) | SMN1; SMN2NPY5RCYP2C19HRH3HTT | |
| SCHEMBL8260249 | 0.75 | HRH3 (0.48) | SMN1; SMN2NPY5RCYP2C19HRH3HTT | |
| SCHEMBL4882807 | 0.75 | HRH3 (0.48) | SMN1; SMN2NPY5RCYP2C19HRH3HTT | |
| SCHEMBL4590999 | 0.75 | NPY5R (0.60) | NPY5RCYP2C19HRH3ALDH1A1POLB | |
| SCHEMBL4365551 | 0.74 | NPY5R (0.58) | NPY5RHRH3TNKSTNKS2ALDH1A1 | |
| SCHEMBL4365548 | 0.74 | NPY5R (0.58) | NPY5RHRH3TNKSTNKS2ALDH1A1 | |
| SCHEMBL21138104 | 0.74 | IDO1 (0.60) | SMN1; SMN2NPY5RHRH3TNKSTNKS2 | |
| SCHEMBL4883090 | 0.72 | IDO1 (0.64) | SMN1; SMN2LMNACYP2C19NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234252-A1 | Compounds Useful in Therapy | PFIZER INC | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234252-A1 | Compounds Useful in Therapy | AVPR1A, AVPR1B, AVPR2 | SMN1; SMN2 2757/4885LMNA 1476/4885NPY5R 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.