Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631512 | 0.91 | BRAF (0.57) | RAF1BRAF | |
| SCHEMBL4878345 | 0.90 | RAF1 (0.53) | RAF1BRAF | |
| SCHEMBL4886254 | 0.88 | MAPK14 (0.47) | RAF1BRAF | |
| SCHEMBL4882776 | 0.82 | BRAF (0.57) | RAF1BRAF | |
| SCHEMBL4631343 | 0.81 | BRAF (0.58) | RAF1BRAF | |
| SCHEMBL30237033 | 0.77 | RAF1 (0.59) | RAF1BRAF | |
| SCHEMBL29272141 | 0.77 | RAF1 (0.59) | RAF1BRAF | |
| SCHEMBL19328020 | 0.76 | RAF1 (0.60) | RAF1BRAF | |
| SCHEMBL4877170 | 0.76 | BRAF (0.63) | RAF1BRAF | |
| SCHEMBL25988162 | 0.74 | RAF1 (0.60) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146570-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2008-06-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146570-A1 | Chemical Compounds | BRAF, RAF1, NRAS | RAF1 2/4885BRAF 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.