Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2543049 | 0.86 | KCNH2 (0.44) | KCNH2SLC2A1JAK2JAK1 | |
| SCHEMBL2543045 | 0.86 | KCNH2 (0.44) | KCNH2SLC2A1JAK2JAK1 | |
| SCHEMBL5726714 | 0.86 | SLC2A1 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL16650256 | 0.85 | KCNH2 (0.43) | KCNH2SLC2A1JAK2JAK1 | |
| SCHEMBL3597040 | 0.85 | KCNH2 (0.43) | KCNH2SLC2A1JAK2JAK1 | |
| SCHEMBL16650254 | 0.85 | KCNH2 (0.43) | KCNH2SLC2A1JAK2JAK1 | |
| SCHEMBL16650253 | 0.85 | KCNH2 (0.43) | KCNH2SLC2A1JAK2JAK1 | |
| SCHEMBL2539625 | 0.84 | KCNH2 (0.42) | KCNH2SLC2A1JAK2JAK1 | |
| SCHEMBL2537316 | 0.84 | KCNH2 (0.42) | KCNH2SLC2A1JAK2JAK1 | |
| SCHEMBL2539623 | 0.84 | KCNH2 (0.42) | KCNH2SLC2A1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987040-A1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093963-A1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-23 | — | — | WO | disclosed |