Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147206 | 1.00 | NTRK1 (0.68) | NTRK1IGF1R | |
| SCHEMBL4077780 | 0.88 | NTRK1 (0.56) | NTRK1IGF1R | |
| SCHEMBL4144052 | 0.84 | NTRK1 (0.60) | NTRK1IGF1R | |
| SCHEMBL4163628 | 0.81 | NTRK1 (1.00) | NTRK1IGF1R | |
| SCHEMBL4151801 | 0.80 | NTRK1 (0.59) | NTRK1IGF1R | |
| SCHEMBL4077805 | 0.76 | NTRK1 (0.69) | NTRK1IGF1R | |
| SCHEMBL4148218 | 0.76 | IGF1R (0.58) | NTRK1IGF1R | |
| SCHEMBL11343024 | 0.76 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4069119 | 0.75 | NTRK1 (0.76) | NTRK1IGF1R | |
| SCHEMBL14050659 | 0.74 | IGF1R (0.70) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877057-A1 | USE OF PYRAZOLYL-PYRIMIDINE DERIVATIVES IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006115452-A1 | USE OF PYRAZOLYL-PYRIMIDINE DERIVATIVES IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | WO | disclosed |