Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795327 | 0.90 | TLR7 (0.37) | TLR7TLR8 | |
| SCHEMBL5348449 | 0.89 | TLR7 (0.38) | TLR7TLR8 | |
| SCHEMBL4872079 | 0.87 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL5344101 | 0.86 | TLR7 (0.35) | TLR7TLR8 | |
| SCHEMBL4794557 | 0.85 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL4873466 | 0.85 | TLR7 (0.45) | TLR7TLR8 | |
| SCHEMBL5338444 | 0.85 | TLR7 (0.36) | TLR7TLR8 | |
| SCHEMBL13914506 | 0.83 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL5339791 | 0.83 | TLR7 (0.37) | TLR7TLR8 | |
| SCHEMBL4792346 | 0.83 | TLR7 (0.43) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |