Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9199538 | 1.00 | FFAR3 (0.50) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL270502 | 1.00 | FFAR3 (0.50) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL11528247 | 0.97 | FFAR3 (0.47) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL11589826 | 0.97 | FFAR3 (0.47) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL3958994 | 0.97 | FFAR3 (0.47) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL8022740 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL3741328 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL17844429 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL1683370 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNGLRA1SLC6A9 | |
| Acetic Acid SCHEMBL598762 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNGLRA1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110343562-A | A kind of water base extraordinary fatty amine highly-efficient lubricant | 广州市君禾实业有限公司 | 2019-10-18 | — | — | CN | claimed |
| CN-109877336-A | A kind of preparation method of flake copper powder | 南京林业大学 | 2019-06-14 | — | — | CN | claimed |
| CN-106398522-A | Anti-fouling compositions comprising silica nanoparticles and functionalized silane compounds and coated articles thereof | 3M创新有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-103025654-B | The preparation method and application of the Graphene that coordinating group is modified | Jining Lite Nano Technology Co.,Ltd. (CN) | 2015-10-14 | — | — | CN | claimed |
| CN-104041362-A | Method for safely producing rice in rice field with serious Cd pollution | AGRO ENVIRONMENTAL PROT INST MINISTRY AGRICULTURE | 2014-09-17 | — | — | CN | claimed |
| CN-101468205-A | Aqueous medicinal composition | PEIXUE LING (CN) | 2009-07-01 | — | — | CN | claimed |
| US-20080064622-A1 | Rinse Solution for Cleaning and Protecting Surfaces | VILLA FRANK L | 2008-03-13 | — | — | US | claimed |
| WO-2006017922-A9 | RINSE SOLUTION FOR CLEANING AND PROTECTING SURFACES | VILLA FRANK L (CA) | 2007-04-12 | — | — | WO | claimed |
| WO-2006017922-A1 | RINSE SOLUTION FOR CLEANING AND PROTECTING SURFACES | VILLA FRANK L (CA) | 2006-02-23 | — | — | WO | claimed |
| CN-1038929-C | Chelating agents with ortho-complexing functionality and methods for preparing complexes thereof | DOW CHEMICAL CO (US) | 1998-07-01 | — | — | CN | claimed |
| CN-1042536-A | Chelating agents with ortho-complexing functionality and methods for preparing complexes thereof | DOW CHEMICAL CO (US) | 1990-05-30 | — | — | CN | claimed |
| CN-110870475-A | Chlorantraniliprole water dispersible granule with high hard water resistance and preparation method thereof | 浙江中山化工集团股份有限公司 | 2020-03-10 | — | — | CN | disclosed |
| CN-109666478-A | A kind of method of purification of oil-soluble quantum dot | TCL集团股份有限公司 | 2019-04-23 | — | — | CN | disclosed |
| EP-3293233-B1 | AQUEOUS PROTECTIVE COATING COMPOSITION FOR CHROMIUM SURFACES | 3M INNOVATIVE PROPERTIES CO (US) | 2019-04-10 | — | — | EP | disclosed |
| CN-106398522-B | Anti-fouling compositions comprising silica nanoparticles and functionalized silane compounds and coated articles thereof | 3M创新有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-1038929-C | Chelating agents with ortho-complexing functionality and methods for preparing complexes thereof | DOW CHEMICAL CO (US) | 1998-07-01 | — | — | CN | disclosed |
| WO-1998008884-A1 | HYDROPHILIC AND HYDROPHOBIC POLYETHER POLYURETHANES AND USES THEREFOR | TYNDALE PLAINS-HUNTER, LTD. (US) | 1998-03-05 | — | — | WO | disclosed |
| CN-1090286-A | Have the difunctionality ligand complex of ortho ligating functionality and the preparation method of conjugate thereof | DOW CHEMICAL CO (US) | 1994-08-03 | — | — | CN | disclosed |
| CN-1042536-A | Chelating agents with ortho-complexing functionality and methods for preparing complexes thereof | DOW CHEMICAL CO (US) | 1990-05-30 | — | — | CN | disclosed |
| CN-1041575-A | Utilize the polyvalent metal soln of controlled-potential electrolysis regeneration chelating | DOW CHEMICAL CO (US) | 1990-04-25 | — | — | CN | disclosed |