Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 7/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876737 | 0.87 | PTGES2 (0.31) | HSP90B1HSP90AA1TRAP1PTGES2 | |
| SCHEMBL4795249 | 0.86 | HSP90B1 (0.38) | HSP90B1HSP90AA1TRAP1SLC40A1KMT2A | |
| SCHEMBL4794260 | 0.85 | HSP90B1 (0.38) | HSP90B1HSP90AA1TRAP1SLC40A1KMT2A | |
| SCHEMBL4880536 | 0.84 | TLR7 (0.35) | HSP90B1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4793669 | 0.83 | HSP90B1 (0.39) | HSP90B1HSP90AA1TRAP1SLC40A1KMT2A | |
| SCHEMBL4880838 | 0.82 | TLR7 (0.35) | HSP90B1HSP90AA1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL4791683 | 0.81 | — | — | |
| SCHEMBL4790940 | 0.80 | — | — | |
| SCHEMBL4792710 | 0.80 | HSP90B1 (0.40) | HSP90B1HSP90AA1TRAP1 | |
| SCHEMBL4883812 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |