Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4881900 | 0.92 | KDM4E (0.56) | KDM4EALDH1A1KMT2AMEN1MAPK1 | |
| Trifluoroacetic Acid SCHEMBL3999368 | 0.88 | P2RY12 (0.59) | KDM4EALDH1A1P2RY12 | |
| Trifluoroacetic Acid SCHEMBL4871542 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1KMT2AMEN1MAPK1 | |
| Trifluoroacetic Acid SCHEMBL5599936 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1KMT2AP2RY12 | |
| Hydrochloric Acid SCHEMBL5270136 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1KMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL4881395 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1KMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL4104473 | 0.78 | P2RY12 (0.61) | KDM4EP2RY12 | |
| Trifluoroacetic Acid SCHEMBL5265543 | 0.77 | P2RY12 (0.51) | KDM4EKMT2AP2RY12 | |
| Trifluoroacetic Acid SCHEMBL4103903 | 0.76 | P2RY12 (0.69) | P2RY12 | |
| SCHEMBL4098247 | 0.74 | KDM4E (0.53) | KDM4EALDH1A1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312208-A1 | Pyridine Analogues | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312208-A1 | Pyridine Analogues | P2RY12, P2RY11, P2RY1 | KDM4E 1759/4885ALDH1A1 1274/4885KMT2A 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.