Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804294 | 0.96 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| Potassium Ion SCHEMBL4810082 | 0.96 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL4813584 | 0.96 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL4812744 | 0.96 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| Tetramethylammonium Ion SCHEMBL4801732 | 0.93 | CYP3A4 (0.47) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL9764741 | 0.82 | CYP3A4 (0.55) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL9764744 | 0.79 | CYP3A4 (0.52) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL7797028 | 0.78 | CYP3A4 (0.53) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| Lithium Ion SCHEMBL29169465 | 0.74 | CYP3A4 (0.70) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL2234240 | 0.72 | CYP3A4 (0.72) | CYP3A4L3MBTL1TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332446-B2 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film and semiconductor device | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-02-19 | — | — | US | disclosed |
| US-20040188809-A1 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film and semiconductor device | SHIN-ETSU CHEMICAL CO., LTD. | 2004-09-30 | — | — | US | disclosed |