SCHEMBL4882575

SCHEMBL4882575

COc1cccc([O])c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
TP53 P04637 2/20 0.64
LMNA P02545 2/20 0.64
CYP3A4 P08684 2/20 0.64
MAPT P10636 2/20 0.64
ALDH1A1 P00352 1/20 0.64
HPGD P15428 1/20 0.64
ALOX15 P16050 1/20 0.64
ALOX12 P18054 1/20 0.64
MAPK1 P28482 1/20 0.64
HSD17B10 Q99714 1/20 0.64
TLR2 O60603 1/20 0.57
ERN1 O75460 1/20 0.57
TLR1 Q15399 1/20 0.57
TLR6 Q9Y2C9 1/20 0.57
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA12 O43570 3/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Syringol SCHEMBL156388 0.83 KDM4E (0.80) KDM4ETP53LMNACYP3A4MAPT
Syringol SCHEMBL28128050 0.81 KDM4E (0.70) KDM4ETP53LMNACYP3A4MAPT
Syringol SCHEMBL8986496 0.80 KDM4E (0.76) KDM4ETP53LMNACYP3A4MAPT
Syringol SCHEMBL6049240 0.80 KDM4E (0.76) KDM4ETP53LMNACYP3A4MAPT
Syringol SCHEMBL7610366 0.80 KDM4E (0.76) KDM4ETP53LMNACYP3A4MAPT
3-Methoxycatechol SCHEMBL67332 0.78 TP53 (1.00) KDM4ETP53LMNACYP3A4MAPT
3-Methoxycatechol SCHEMBL29477155 0.78 TP53 (1.00) KDM4ETP53LMNACYP3A4MAPT
Syringol SCHEMBL28085163 0.77 ERN1 (0.68) KDM4ETP53LMNACYP3A4MAPT
SCHEMBL714204 0.76 CA1 (0.50) KDM4ETP53LMNACYP3A4MAPT
Syringol SCHEMBL20564590 0.76 KDM4E (0.70) KDM4ETP53LMNACYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410925-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-08-12 US disclosed
US-7202316-B2 Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-10 US disclosed
US-7115539-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2006-10-03 US disclosed
US-7008897-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-07 US disclosed
US-20060030480-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2006-02-09 US disclosed
US-20050192178-A1 Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-09-01 US disclosed
US-20040209763-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed
US-20040209762-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209762-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer AP1M1, PYM1, SEM1 KDM4E 1556/4885TP53 4741/4885LMNA 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.