SCHEMBL4882614

SCHEMBL4882614

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nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.58
LMNA P02545 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
USP2 O75604 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
KDM4E B2RXH2 2/20 0.37
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1326070 0.98 PDE4A (0.60) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL4395508 0.98 PDE4A (0.60) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL28017308 0.98 PDE4A (0.60) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL12017309 0.95 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL11232983 0.89 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL26670440 0.89 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL7555757 0.88 PDE4A (0.50) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL28341676 0.88 PDE4A (0.50) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL16144871 0.88 PDE4A (0.50) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL5471746 0.88 PDE4A (0.50) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106631779-B Polyol esters and their use in processing halogenated vinyl polymers 济南金昌树新材料科技有限公司 2020-07-14 CN disclosed
US-8865229-B2 Marrubiin and composition for reducing snoring, package and method PURANOX MEDICAL B.V. (NL) 2014-10-21 US disclosed
US-20110305780-A1 Marrubiin and composition for reducing snoring, package and method PURANOX MEDICAL B.V. (NL) 2011-12-15 US disclosed
US-20080305192-A1 Marrubiin and Composition For Reducing Snoring, Package and Method PURANOX MEDICAL B.V. (NL) 2008-12-11 US disclosed
CN-1427013-A Self-viscous cationic or amphoteric free-radical polymer and their use in cosmetics OREAL (FR) 2003-07-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305192-A1 Marrubiin and Composition For Reducing Snoring, Package and Method NISCH, UTRN, MTPN PDE4A 217/4885LMNA 1330/4885L3MBTL1 4081/4885
US-20110305780-A1 Marrubiin and composition for reducing snoring, package and method NISCH, UTRN, MTPN PDE4A 172/4885LMNA 1451/4885L3MBTL1 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.