SCHEMBL4883353

SCHEMBL4883353

CC1CCCC(=O)C1.CC1CCCC1=O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA4 P22748 1/20 0.61
KMT2A Q03164 1/20 0.59
THRB P10828 1/20 0.36
TLR4 O00206 1/20 0.33
MAPT P10636 1/20 0.33
NOS3 P29474 2/20 0.31
NOS1 P29475 2/20 0.31
NOS2 P35228 2/20 0.31
CYP3A4 P08684 1/20 0.31
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
POLB P06746 1/20 0.30
CBR1 P16152 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11862985 0.96 CA1 (0.69) CA1CA2CA4KMT2ATHRB
SCHEMBL17634338 0.92 KMT2A (0.73) CA1CA2CA4KMT2ATHRB
SCHEMBL27622 0.89 CA1 (0.60) CA1CA2CA4KMT2ATHRB
SCHEMBL857124 0.89
SCHEMBL22708 0.89
SCHEMBL38785 0.89
Water SCHEMBL28084183 0.87
SCHEMBL4176635 0.84
SCHEMBL3486322 0.84
SCHEMBL106582 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7468463-B2 Method for producing optically active carbonyl compounds BASF AG (DE) 2008-12-23 US claimed