SCHEMBL4883554

SCHEMBL4883554

CCCCNS(=O)(=O)CCCCCn1c(C(C)OC)nc2c(N)nc(C)c(C)c21

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 3/20 0.34
RELA Q04206 4/20 0.33
TLR8 Q9NR97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4871676 0.89
SCHEMBL4794600 0.89 KDM4E (0.32) TLR7TLR8
SCHEMBL4791004 0.88 KDM4E (0.30) TLR7TLR8
SCHEMBL4793944 0.86 TLR7 (0.30) TLR7
SCHEMBL4794368 0.85 TLR7 (0.31) TLR7
SCHEMBL4876206 0.84
SCHEMBL4881712 0.83 TLR7 (0.34) TLR7
SCHEMBL4791567 0.82
SCHEMBL4883559 0.81 TLR7 (0.40) TLR7TLR8
SCHEMBL4793062 0.81 TLR7 (0.32) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1513524-A4 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2008-09-03 EP disclosed
EP-1513524-A2 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M Innovative Properties Company (US) 2005-03-16 EP disclosed
WO-2003103584-A2 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-12-18 WO disclosed