SCHEMBL4883694

SCHEMBL4883694

C=CC(=O)OC(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.37
ALDH1A1 P00352 4/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP3A4 P08684 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11592647 0.81 HCAR2 (0.38)
SCHEMBL11592654 0.81 HCAR2 (0.38)
SCHEMBL11693680 0.81 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30307070 0.80 TSHR (0.38) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL11628351 0.80 TSHR (0.35) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL7646494 0.80 TSHR (0.35) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL11595662 0.79
SCHEMBL11595664 0.79
SCHEMBL11594380 0.77 HCAR2 (0.31)
SCHEMBL11595668 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113201089-A All-solid-state self-repairing ion conductor, preparation method thereof and ion device 香港中文大学(深圳) 2021-08-03 CN claimed
US-8648160-B2 Optical semiconductor sealing material IDEMITSU KOSAN CO., LTD. (JP) 2014-02-11 US claimed
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP claimed
US-4268607-A Method of patterning a resist layer for manufacture of a semiconductor element VLSI TECHNOLOGY RESEARCH ASSOCIATION (JP) 1981-05-19 US claimed
US-11912860-B2 Highly loaded inorganic filled organic resin systems CORNING INCORPORATED (US) 2024-02-27 US disclosed
US-11674030-B2 Highly loaded inorganic filled aqueous resin systems CORNING INCORPORATED (US) 2023-06-13 US disclosed
CN-111433268-B Highly loaded inorganic filled waterborne resin systems 康宁股份有限公司 2022-07-05 CN disclosed
CN-113201089-A All-solid-state self-repairing ion conductor, preparation method thereof and ion device 香港中文大学(深圳) 2021-08-03 CN disclosed
CN-111971336-A Highly loaded inorganic filled organic resin systems 康宁股份有限公司 2020-11-20 CN disclosed
CN-111433268-A Highly loaded inorganic filled waterborne resin systems 康宁股份有限公司 2020-07-17 CN disclosed
US-8648160-B2 Optical semiconductor sealing material IDEMITSU KOSAN CO., LTD. (JP) 2014-02-11 US disclosed
US-20120305982-A1 OPTICAL SEMICONDUCTOR SEALING MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2012-12-06 US disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
US-4268607-A Method of patterning a resist layer for manufacture of a semiconductor element VLSI TECHNOLOGY RESEARCH ASSOCIATION (JP) 1981-05-19 US disclosed
US-4061829-A Negative resist for X-ray and electron beam lithography and method of using same BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1977-12-06 US disclosed
US-3954683-A 1,2,2,2-Tetrachlorethyl acrylate and methacrylate polymers and copolymers CESKOSLOVENSKA AKADEMIE VED (CS) 1976-05-04 US disclosed
US-3954683-A 1,2,2,2-Tetrachlorethyl acrylate and methacrylate polymers and copolymers CESKOSLOVENSKA AKADEMIE VED (CS) 1976-05-04 US disclosed
US-3882169-A 1,2,2,2,-Tetrachlorethyl acrylate and methacrylate CESKOSLOVENSKA AKADEMIE VED 1975-05-06 US disclosed