⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264291 | 0.78 | — | — | |
| SCHEMBL12033681 | 0.76 | — | — | |
| SCHEMBL16836793 | 0.72 | — | — | |
| SCHEMBL16093525 | 0.65 | — | — | |
| SCHEMBL1199564 | 0.65 | — | — | |
| SCHEMBL8119262 | 0.63 | — | — | |
| SCHEMBL12559414 | 0.60 | — | — | |
| SCHEMBL12559294 | 0.60 | CA1 (0.36) | — | |
| SCHEMBL6454776 | 0.60 | — | — | |
| SCHEMBL14154832 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160015786-A1 | MOBILIZING AGENTS AND USES THEREFOR | MATER MEDICAL RESEARCH INSTITUTE LIMITED (AU) | 2016-01-21 | — | — | US | disclosed |
| EP-2961398-A1 | MOBILIZING AGENTS AND USES THEREFOR | Mater Medical Research Institute Limited (AU) | 2016-01-06 | — | — | EP | disclosed |
| US-8980903-B2 | Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors | AMGEN INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140350244-A1 | FUSED PYRIDINE, PYRIMIDINE AND TRIAZINE COMPOUNDS AS CELL CYCLE INHIBITORS | AMGEN INC (US) | 2014-11-27 | — | — | US | disclosed |
| US-8841312-B2 | Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors | AMGEN INC. (US) | 2014-09-23 | — | — | US | disclosed |
| WO-2014132100-A1 | MOBILIZING AGENTS AND USES THEREFOR | MATER MEDICAL RESEARCH INSTITUTE LIMITED (AU) | 2014-09-04 | — | — | WO | disclosed |
| EP-2278973-B1 | GEM-DISUBSTITUTED AND SPIROCYCLIC AMINO PYRIDINES/PYRIMIDINES AS CELL CYCLE INHIBITORS | AMGEN INC (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20110097305-A1 | Gem-Disubstituted and Spirocyclic Amino Pyridines/Pyrimidines as Cell Cycle Inhibitors | AMGEN INC. (US) | 2011-04-28 | — | — | US | disclosed |
| US-20080213404-A1 | Hif Modulating Compounds and Methods of Use Thereof | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO | 2008-09-04 | — | — | US | disclosed |
| WO-2006084210-A9 | HIF MODULATING COMPOUNDS AND METHODS OF USE THEREOF | UNIV CALIFORNIA SAN DIEGO (US) | 2006-10-26 | — | — | WO | disclosed |
| WO-2006084210-A2 | HIF MODULATING COMPOUNDS AND METHODS OF USE THEREOF | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2006-08-10 | — | — | WO | disclosed |