Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430407 | 0.99 | UTS2R (0.45) | UTS2RDRD2TP53MAPTLMNA | |
| SCHEMBL4428009 | 0.99 | UTS2R (0.45) | UTS2RDRD2TP53MAPTLMNA | |
| SCHEMBL4440091 | 0.95 | UTS2R (0.45) | UTS2RDRD2TP53MAPTLMNA | |
| SCHEMBL4437169 | 0.91 | UTS2R (0.41) | UTS2RDRD2LMNA | |
| SCHEMBL4431597 | 0.90 | UTS2R (0.58) | UTS2RTP53MAPTLMNA | |
| SCHEMBL4428025 | 0.90 | UTS2R (0.35) | UTS2RDRD2TP53MAPTLMNA | |
| SCHEMBL4437091 | 0.88 | UTS2R (0.59) | UTS2RTP53MAPTLMNA | |
| SCHEMBL4433536 | 0.88 | UTS2R (0.45) | UTS2RTP53MAPTLMNA | |
| SCHEMBL4430255 | 0.87 | UTS2R (0.38) | UTS2RLMNA | |
| SCHEMBL4426624 | 0.87 | UTS2R (0.44) | UTS2RTP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759342-B2 | Benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one urotensin II receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2014-06-24 | — | — | US | claimed |
| US-20080039454-A1 | Urotensin II receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-02-14 | — | — | US | claimed |
| US-8759342-B2 | Benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one urotensin II receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2014-06-24 | — | — | US | disclosed |
| US-20080039454-A1 | Urotensin II receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039454-A1 | Urotensin II receptor antagonists | UTS2R, PLAUR, NTSR2 | UTS2R 1/4885DRD2 731/4885TP53 4636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.