Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 9/20 | 0.68 |
| ▸ | CSF1R | P07333 | 4/20 | 0.68 |
| ▸ | PIKFYVE | Q9Y2I7 | 2/20 | 0.67 |
| ▸ | ABL1 | P00519 | 5/20 | 0.59 |
| ▸ | BCR | P11274 | 4/20 | 0.59 |
| ▸ | TEK | Q02763 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.57 |
| ▸ | PRKCA | P17252 | 3/20 | 0.57 |
| ▸ | ESYT2 | A0FGR8 | 2/20 | 0.57 |
| ▸ | NBAS | A2RRP1 | 2/20 | 0.57 |
| ▸ | CNOT1 | A5YKK6 | 2/20 | 0.57 |
| ▸ | TBKBP1 | A7MCY6 | 2/20 | 0.57 |
| ▸ | AGPS | O00116 | 2/20 | 0.57 |
| ▸ | MYO1F | O00160 | 2/20 | 0.57 |
| ▸ | SNAP23 | O00161 | 2/20 | 0.57 |
| ▸ | AP3B1 | O00203 | 2/20 | 0.57 |
| ▸ | PSMD12 | O00232 | 2/20 | 0.57 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.57 |
| ▸ | PGRMC1 | O00264 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630979 | 0.92 | BRAF (0.68) | BRAFCSF1RPIKFYVEABL1TEK | |
| SCHEMBL27708222 | 0.90 | PIKFYVE (0.55) | BRAFCSF1RPIKFYVEABL1BCR | |
| SCHEMBL15976959 | 0.89 | BRAF (0.58) | BRAFCSF1RPIKFYVETEKPDGFRB | |
| SCHEMBL1408815 | 0.86 | ABL1 (0.77) | BRAFCSF1RPIKFYVEABL1BCR | |
| SCHEMBL1415439 | 0.84 | ABL1 (0.74) | BRAFCSF1RPIKFYVEABL1BCR | |
| SCHEMBL715868 | 0.84 | ABL1 (0.69) | BRAFCSF1RPIKFYVEABL1BCR | |
| SCHEMBL5481076 | 0.82 | ABL1 (0.63) | BRAFCSF1RPIKFYVEABL1BCR | |
| SCHEMBL544069 | 0.82 | PIKFYVE (0.69) | BRAFCSF1RPIKFYVEABL1BCR | |
| SCHEMBL22024555 | 0.82 | PIKFYVE (0.80) | BRAFCSF1RPIKFYVEABL1BCR | |
| SCHEMBL22024547 | 0.82 | PIKFYVE (0.65) | BRAFCSF1RPIKFYVEABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014128213-A1 | COMPOUNDS FOR USE IN INHIBITING HIV CAPSID ASSEMBLY | Ruprecht-Karls-Universität Heidelberg (DE) | 2014-08-28 | — | — | WO | disclosed |
| US-20080146570-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146570-A1 | Chemical Compounds | BRAF, RAF1, NRAS | BRAF 1/4885CSF1R 1706/4885PIKFYVE 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.