Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MTTP | P55157 | 14/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102276 | 1.00 | TDP1 (0.56) | TDP1MTTPMEN1KMT2A | |
| SCHEMBL4939844 | 0.82 | TDP1 (0.69) | TDP1MTTPMEN1KMT2A | |
| SCHEMBL14046234 | 0.78 | TDP1 (0.71) | TDP1MTTPMEN1KMT2A | |
| SCHEMBL14046208 | 0.78 | TDP1 (0.59) | TDP1MTTPMEN1KMT2A | |
| SCHEMBL14028030 | 0.76 | MTTP (0.58) | TDP1MTTP | |
| SCHEMBL4788125 | 0.75 | TDP1 (0.59) | TDP1MTTPMEN1KMT2A | |
| SCHEMBL4941179 | 0.75 | TDP1 (0.59) | TDP1MTTPMEN1KMT2A | |
| SCHEMBL4938920 | 0.75 | MTTP (0.59) | MTTP | |
| SCHEMBL4938915 | 0.75 | MTTP (0.59) | MTTP | |
| SCHEMBL4940392 | 0.74 | MTTP (0.58) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100423-A1 | GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |