Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237062 | 0.90 | SMN1; SMN2 (0.42) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL4233951 | 0.88 | SMN1; SMN2 (0.40) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL4242223 | 0.88 | MEN1 (0.37) | MEN1KMT2ALMNASMN1; SMN2NPSR1 | |
| SCHEMBL4240249 | 0.87 | SMN1; SMN2 (0.45) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4888299 | 0.86 | MCHR1 (0.37) | LMNAMAPTSMN1; SMN2NPSR1MCHR1 | |
| SCHEMBL4236550 | 0.83 | MCHR1 (0.40) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL4683606 | 0.83 | HRH3 (0.42) | MCHR1 | |
| SCHEMBL4238883 | 0.82 | MCHR1 (0.43) | MEN1KMT2ALMNASMN1; SMN2NPSR1 | |
| SCHEMBL4236062 | 0.82 | MCHR1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4233894 | 0.82 | MCHR1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |