Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623843 | 1.00 | TSHR (0.50) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL10395574 | 1.00 | TSHR (0.50) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL10036756 | 1.00 | TSHR (0.50) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL9309570 | 1.00 | TSHR (0.50) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL6441826 | 1.00 | — | — | |
| SCHEMBL23921312 | 1.00 | TSHR (0.50) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL15450555 | 1.00 | TSHR (0.50) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL17873397 | 1.00 | TSHR (0.50) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL13356338 | 1.00 | — | — | |
| SCHEMBL2045337 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831096-A | VARYING THERMAL STABILITIES | PENNWALT CORPORATION (US) | 1989-05-16 | — | — | US | claimed |
| US-7364792-B2 | Spun-dyed polyurethaneurea fibres, a process for their production and their use for producing fabrics | DORLASTAN FIBERS GMBH (DE) | 2008-04-29 | — | — | US | disclosed |
| US-20060210794-A1 | Spun-dyed polyurethaneurea fibres, a process for their production and their use for producing fabrics | DORLASTAN FIBERS GMBH | 2006-09-21 | — | — | US | disclosed |
| US-6919413-B2 | Imino-amide catalyst compositions for the polymerization of olefins | UNIVATION TECHNOLOGIES, LLC (US) | 2005-07-19 | — | — | US | disclosed |
| US-6919467-B2 | Imino-amide catalyst compositions for the polymerization of olefins | UNIVATION TECHNOLOGIES, LLC (US) | 2005-07-19 | — | — | US | disclosed |
| CN-1589284-A | Imino-amide catalyst compositions for the polymerization of olefins | UNIVATION TECH LLC (US) | 2005-03-02 | — | — | CN | disclosed |
| EP-1456252-A1 | IMINO-AMIDE CATALYST COMPOSITIONS FOR THE POLYMERIZATION OF OLEFINS | Univation Technologies LLC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20030191012-A1 | Imino-amide catalyst compositions for the polymerization of olefins | MURRAY REX EUGENE (US) | 2003-10-09 | — | — | US | disclosed |
| US-20030171206-A1 | Imino-amide catalyst compositions for the polymerization of olefins | UNIVATION TECHNOLOGIES, LLC | 2003-09-11 | — | — | US | disclosed |
| WO-2003051935-A1 | IMINO-AMIDE CATALYST COMPOSITIONS FOR THE POLYMERIZATION OF OLEFINS | UNIVATION TECHNOLOGIES, LLC (US) | 2003-06-26 | — | — | WO | disclosed |
| US-5232484-A | Aqueous acid solution; mineralization; absence of large concentrations of organic solvents, chloride and sulfate | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 1993-08-03 | — | — | US | disclosed |