SCHEMBL4886293

SCHEMBL4886293

Cn1ncnc1[C@@H](CC(=O)O)c1ccc(OCc2cc(-c3ccccc3)ccc2C(F)(F)F)cc1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4767757 0.88 FFAR1 (0.59) FFAR1
SCHEMBL3549387 0.83 FFAR1 (0.76) FFAR1
SCHEMBL3549383 0.83 FFAR1 (0.76) FFAR1
SCHEMBL4742258 0.78 FFAR1 (0.61) FFAR1
SCHEMBL4681518 0.78 FFAR1 (0.61) FFAR1
SCHEMBL12021112 0.76 FFAR1 (0.68) FFAR1
SCHEMBL4737595 0.75 FFAR1 (0.60) FFAR1
SCHEMBL4740999 0.75 FFAR1 (0.60) FFAR1
SCHEMBL4684935 0.74 FFAR1 (0.66) FFAR1
SCHEMBL4684942 0.74 FFAR1 (0.66) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1893582-A2 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE IN TREATING METABOLIC DISORDERS Amgen, Inc (US) 2008-03-05 EP disclosed
WO-2006127503-A2 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE IN TREATING METABOLIC DISORDERS AMGEN INC (US) 2006-11-30 WO disclosed