Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | ACSL5 | Q9ULC5 | 1/20 | 0.42 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269570 | 0.92 | ADORA2A (0.63) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL4884280 | 0.90 | ADORA2A (0.58) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14294289 | 0.90 | ADORA2A (0.44) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14269539 | 0.87 | ADORA2A (0.55) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14269571 | 0.86 | ADORA2A (0.56) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14269531 | 0.86 | ADORA2A (0.53) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14269537 | 0.86 | ADORA2A (0.53) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14269542 | 0.86 | ADORA2A (0.53) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14269538 | 0.86 | ADORA2A (0.53) | ADORA2AADORA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14269521 | 0.86 | MAPK14 (0.61) | ADORA2AADORA1ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051416-A1 | Novel Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080051416-A1 | Novel Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080051416-A1 | Novel Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051416-A1 | Novel Compounds | MAPK1, MAPKAPK2, MAPK6 | ADORA2A 2555/4885ADORA1 3092/4885ALDH1A1 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.