Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 16/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795050 | 1.00 | MCHR1 (0.52) | MCHR1KCNH2CYP3A4DPP4 | |
| SCHEMBL4796258 | 0.91 | MCHR1 (0.47) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL4879854 | 0.91 | MCHR1 (0.47) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL4886169 | 0.91 | MCHR1 (0.64) | MCHR1KCNH2DPP4 | |
| SCHEMBL1779304 | 0.86 | MCHR1 (0.50) | MCHR1KCNH2 | |
| Hydrochloric Acid SCHEMBL4728285 | 0.86 | MCHR1 (0.49) | MCHR1KCNH2DPP4 | |
| Hydrochloric Acid SCHEMBL4728290 | 0.86 | MCHR1 (0.49) | MCHR1KCNH2DPP4 | |
| SCHEMBL4881952 | 0.85 | MCHR1 (0.54) | MCHR1KCNH2CYP3A4 | |
| SCHEMBL4796931 | 0.85 | MCHR1 (0.49) | MCHR1KCNH2DPP4 | |
| SCHEMBL4729454 | 0.84 | MCHR1 (0.49) | MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | PFIZER INC | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | MCHR1, MCHR2, MC1R | MCHR1 1/4885KCNH2 3042/4885CYP3A4 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.