SCHEMBL4888147

SCHEMBL4888147

CCOCCCOC(=O)C=CC#N

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.48
HCAR2 Q8TDS4 5/20 0.43
MAPT P10636 2/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 3/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 3/20 0.37
APP P05067 2/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL462001 0.89 TSHR (0.48) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4892566 0.88 ATM (0.52) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4888251 0.88 ATM (0.61) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4889687 0.88 TSHR (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL6466648 0.86 HCAR2 (0.54) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10395630 0.85 ATM (0.65) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4892532 0.85 ATM (0.61) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL24797 0.84 ATM (0.70) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3207425 0.83 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4890474 0.82 ATM (0.39) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115362230-A Low odor cyanoacrylate compositions 汉高股份有限及两合公司 2022-11-18 CN disclosed
CN-113874459-A Flexible photocurable cyanoacrylate compositions 汉高知识产权控股有限责任公司 2021-12-31 CN disclosed
US-20080293872-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-27 US disclosed
US-20080287574-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-20 US disclosed