SCHEMBL4890239

SCHEMBL4890239

CSCCC(=O)NC(C)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.79
KMT2A Q03164 5/20 0.61
MEN1 O00255 3/20 0.61
GPR139 Q6DWJ6 2/20 0.56
ALDH1A1 P00352 4/20 0.54
HPGD P15428 2/20 0.54
GAA P10253 2/20 0.54
HTT P42858 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
NPC1 O15118 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9516620 0.89 MAPT (0.82) MAPTKMT2AMEN1GPR139ALDH1A1
SCHEMBL6399827 0.84 MAPT (0.75) MAPTKMT2AMEN1GPR139ALDH1A1
SCHEMBL6399316 0.84 MAPT (0.75) MAPTKMT2AMEN1GPR139ALDH1A1
SCHEMBL13511957 0.82 MAPT (0.55) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL23080142 0.81 MAPT (0.71) MAPTKMT2AMEN1GPR139ALDH1A1
SCHEMBL3069332 0.81 MAPT (0.71) MAPTKMT2AMEN1GPR139ALDH1A1
SCHEMBL18241727 0.81 MAPT (0.71) MAPTKMT2AMEN1GPR139ALDH1A1
SCHEMBL3076773 0.81 MAPT (0.71) MAPTKMT2AMEN1GPR139ALDH1A1
SCHEMBL16975095 0.81 MAPT (0.71) MAPTKMT2AMEN1GPR139ALDH1A1
SCHEMBL692819 0.81 MAPT (0.71) MAPTKMT2AMEN1GPR139ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US claimed
EP-1853352-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'Oréal (FR) 2007-11-14 EP claimed
WO-2006079568-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'OREAL (FR) 2006-08-03 WO claimed
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US disclosed
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US disclosed
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof L'OREAL (FR) 2008-01-31 US disclosed
EP-1853352-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'Oréal (FR) 2007-11-14 EP disclosed
WO-2006079568-A2 USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF L'OREAL (FR) 2006-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080025940-A1 Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof KRT18, TYR, MC1R MAPT 1733/4885KMT2A 579/4885MEN1 4162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.