Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825469 | 1.00 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3820274 | 1.00 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL2407683 | 0.90 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL2407682 | 0.90 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL2407677 | 0.90 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL2407676 | 0.90 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL1129696 | 0.89 | GSK3B (0.57) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL2403507 | 0.88 | GSK3B (0.52) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL2403505 | 0.88 | GSK3B (0.52) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3819008 | 0.86 | GSK3B (0.49) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452897-B2 | Use of substituted 2-(diaza-bicyclo-alkyl)-pyrimidone derivatives for the treatment of neurodegenerative diseases | SANOFI-AVENTIS (FR) | 2008-11-18 | — | — | US | claimed |