Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 20/20 | 0.52 |
| ▸ | MERTK | Q12866 | 20/20 | 0.52 |
| ▸ | MET | P08581 | 18/20 | 0.52 |
| ▸ | TYRO3 | Q06418 | 15/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110868 | 0.92 | AXL (0.51) | AXLMERTKMETTYRO3 | |
| SCHEMBL3109231 | 0.92 | AXL (0.51) | AXLMERTKMETTYRO3 | |
| SCHEMBL4888298 | 0.91 | AXL (0.54) | AXLMERTKMETTYRO3 | |
| SCHEMBL3101335 | 0.91 | AXL (0.54) | AXLMERTKMETTYRO3 | |
| SCHEMBL3097910 | 0.91 | AXL (0.54) | AXLMERTKMETTYRO3 | |
| SCHEMBL3106986 | 0.85 | AXL (0.55) | AXLMERTKMETTYRO3 | |
| SCHEMBL3101377 | 0.83 | AXL (0.59) | AXLMERTKMETTYRO3 | |
| Trifluoroacetic Acid SCHEMBL3097519 | 0.83 | AXL (0.53) | AXLMERTKMETTYRO3 | |
| Trifluoroacetic Acid SCHEMBL3101354 | 0.83 | AXL (0.53) | AXLMERTKMETTYRO3 | |
| SCHEMBL3104410 | 0.82 | AXL (0.59) | AXLMERTKMETTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001880-A2 | HETEROBICYCLIC PYRAZOLE COMPOUNDS AND METHODS OF USE | Array Biopharma, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007103308-A2 | HETEROBICYCLIC PYRAZOLE COMPOUNDS AND METHODS OF USE | ARRAY BIOPHARMA INC. (US) | 2007-09-13 | — | — | WO | disclosed |