Butachlor

Butachlor

SCHEMBL4891145

CCCCOCN(C(=O)CCl)c1c(CC)cccc1CC.CCCCOCN(C(=O)CCl)c1c(CC)cccc1CC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
TP53 P04637 6/20 0.68
ALDH1A1 P00352 4/20 0.66
NR1I2 O75469 1/20 0.66
CYP3A4 P08684 1/20 0.66
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
PAX8 Q06710 2/20 0.44
JAK2 O60674 1/20 0.44
GPX4 P36969 1/20 0.42
TSHR P16473 3/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 1/20 0.39
THRB P10828 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butachlor SCHEMBL65784 1.00 TDP1 (1.00) TDP1MEN1KMT2ATP53ALDH1A1
Butachlor SCHEMBL11052762 0.95 TDP1 (0.90) TDP1MEN1KMT2ATP53ALDH1A1
Butachlor SCHEMBL17110610 0.94 TDP1 (0.88) TDP1MEN1KMT2ATP53ALDH1A1
SCHEMBL9614001 0.92 TDP1 (0.85) TDP1MEN1KMT2ATP53ALDH1A1
Butachlor SCHEMBL23242441 0.92 TDP1 (0.84) TDP1MEN1KMT2ATP53ALDH1A1
Butachlor SCHEMBL8846427 0.92 TDP1 (0.84) TDP1MEN1KMT2ATP53ALDH1A1
SCHEMBL10780632 0.90 KMT2A (0.81) TDP1MEN1KMT2ATP53ALDH1A1
SCHEMBL9613872 0.89 TDP1 (0.80) TDP1MEN1KMT2ATP53ALDH1A1
SCHEMBL8734929 0.88 NR1I2 (0.85) TDP1MEN1KMT2ATP53ALDH1A1
Butachlor SCHEMBL8343198 0.88 TDP1 (0.77) TDP1MEN1KMT2ATP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746505-B1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORP (US) 2024-06-26 EP disclosed
US-20240124709-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2024-04-18 US disclosed
US-11884821-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2024-01-30 US disclosed
US-11208557-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2021-12-28 US disclosed
US-20210024751-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORPORATION 2021-01-28 US disclosed
US-20200369866-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME ROHM AND HAAS COMPANY 2020-11-26 US disclosed
US-10836908-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2020-11-17 US disclosed
EP-3704189-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME Dow Silicones Corporation (US) 2020-09-09 EP disclosed
US-20200216668-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2020-07-09 US disclosed
EP-2785454-B1 HYDROSILYLATION REACTION CATALYSTS AND CURABLE COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE DOW SILICONES CORP (US) 2019-10-09 EP disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
EP-0590045-A1 SUBSTITUTED PYRIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-04-06 EP disclosed
WO-1992022203-A1 SUBSTITUTED PYRIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-23 WO disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed
WO-1992010501-A1 HERBICIDAL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO disclosed
WO-1992009578-A1 SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-11 WO disclosed
WO-1992004827-A1 HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 WO disclosed
EP-0463054-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 EP disclosed
WO-1990010634-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-20 WO disclosed
EP-0086747-B1 PHENOXY-PHENOXY-ALKANOYL-THIOAMIDES AS HERBICIDES CIBA-GEIGY AG (CH) 1987-01-07 EP disclosed