SCHEMBL4891428

SCHEMBL4891428

[KH].c1ccc(-n2cnc3ccccc32)cc1

nearest known ligand 0.96

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.96
FGFR1 P11362 7/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157265 0.98 HTT (1.00) HTTFGFR1
Benzene SCHEMBL14876970 0.98 HTT (1.00) HTTFGFR1
SCHEMBL467858 0.96 HTT (0.96) HTTFGFR1
SCHEMBL27724758 0.96 HTT (0.96) HTTFGFR1
Iodide SCHEMBL30645138 0.96 HTT (0.96) HTTFGFR1
SCHEMBL30402227 0.91 HTT (0.88) HTTFGFR1
SCHEMBL3419279 0.91 HTT (0.88) HTTFGFR1
SCHEMBL21647144 0.90 HTT (0.85) HTTFGFR1
Bicarbonate SCHEMBL2334509 0.90 HTT (0.85) HTTFGFR1
Bromobenzene SCHEMBL28699914 0.89 HTT (0.82) HTTFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11986547-B2 Cosmetic composition comprising silicone materials DOW SILICONES CORPORATION (US) 2024-05-21 US disclosed
US-11359167-B2 Fabric-care composition comprising silicone materials DOW SILICONES CORPORATION (US) 2022-06-14 US disclosed
US-20200337981-A1 COSMETIC COMPOSITION COMPRISING SILICONE MATERIALS DOW SILICONES CORPORATION 2020-10-29 US disclosed
US-20200339915-A1 FABRIC-CARE COMPOSITION COMPRISING SILICONE MATERIALS DOW SILICONES CORPORATION 2020-10-29 US disclosed
EP-3727597-A1 COSMETIC COMPOSITION COMPRISING SILICONE MATERIALS Dow Silicones Corporation (US) 2020-10-28 EP disclosed
EP-3728539-A1 FABRIC-CARE COMPOSITION COMPRISING SILICONE MATERIALS Dow Silicones Corporation (US) 2020-10-28 EP disclosed
US-20180071190-A1 COSMETIC PRODUCT AND CONCENTRATE FOR PRODUCING THE COSMETIC PRODUCT GCT GMBH (DE) 2018-03-15 US disclosed
US-20080118734-A1 Coating Compositions DOW CORNING IRELAND LTD. (IE) 2008-05-22 US disclosed
WO-2007090759-A1 COPOLYMERS AND THEIR USE AS RHEOLOGY MODIFIER CIBA HOLDING INC. (CH) 2007-08-16 WO disclosed
EP-1744836-A2 PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METHOD OR APPARATUS Dow Corning Ireland Limited (IE) 2007-01-24 EP disclosed
WO-2005110626-A2 PROCESS AND APPARATUS FOR PLASMA COATING, SUBSTRATES COATED BY THIS METOD OR APPARATUS DOW CORNING IRELAND LIMITED (IE) 2005-11-24 WO disclosed