Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24304537 | 0.85 | HTR1D (0.42) | APPTLR9TLR8TLR7OPRL1 | |
| SCHEMBL9731082 | 0.80 | ASAH1 (0.39) | APPTLR9TLR8TLR7QDPR | |
| SCHEMBL4975027 | 0.79 | GRM2 (0.47) | APPOPRL1DRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9731533 | 0.79 | ASAH1 (0.39) | TLR9TLR8TLR7QDPRHTR1D | |
| SCHEMBL9731074 | 0.79 | ACKR3 (0.38) | APPTLR9TLR8TLR7OPRL1 | |
| SCHEMBL13993850 | 0.78 | APP (0.44) | APPTLR9TLR8TLR7OPRL1 | |
| SCHEMBL14924438 | 0.78 | OPRL1 (0.46) | APPTLR9TLR8TLR7OPRL1 | |
| Hydrochloric Acid SCHEMBL9731220 | 0.78 | ACKR3 (0.38) | APPTLR9TLR8TLR7OPRL1 | |
| SCHEMBL24309549 | 0.77 | CYP1A2 (0.55) | APPOPRL1QDPRCYP1A2CYP3A4 | |
| SCHEMBL5005427 | 0.77 | HTR1D (0.55) | APPTLR9TLR8TLR7OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | APP 4868/4885TLR9 4629/4885TLR8 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.