SCHEMBL4892593

SCHEMBL4892593

CCCCCc1nc2cc(C)nn2c(N)c1CCCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 2/20 0.35
HPGD P15428 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
KMT2A Q03164 1/20 0.35
USP2 O75604 1/20 0.34
TSHR P16473 1/20 0.34
MAOB P27338 1/20 0.34
DPP4 P27487 1/20 0.34
TLR7 Q9NYK1 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PIK3CG P48736 1/20 0.33
PKM P14618 1/20 0.33
POLB P06746 1/20 0.33
AURKA O14965 1/20 0.33
KDR P35968 1/20 0.33
AURKB Q96GD4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4921299 0.97 KDM4E (0.40) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL4918926 0.97 KDM4E (0.40) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL4918063 0.97 KDM4E (0.40) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL4910627 0.97 KDM4E (0.40) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL14113724 0.96 KDM4E (0.41) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL14182277 0.96 KDM4E (0.43) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL4923190 0.94 KDM4E (0.40) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL4913865 0.94 KDM4E (0.40) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL4918451 0.94 KDM4E (0.40) KDM4ENPC1HPGDRAB9ASMN1; SMN2
SCHEMBL4917607 0.94 KDM4E (0.40) KDM4ENPC1HPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080125445-A1 5,6-Dialkyl-7-Amino-Azolopyrimidines, Method For Their Production, Their Use For Controlling Pathogenic Fungi and Agents Containing Said Compounds BASF AKTIENGESELLSCHAFT (DE) 2008-05-29 US disclosed
US-20080125445-A1 5,6-Dialkyl-7-Amino-Azolopyrimidines, Method For Their Production, Their Use For Controlling Pathogenic Fungi and Agents Containing Said Compounds BASF AKTIENGESELLSCHAFT (DE) 2008-05-29 US disclosed
US-20080125445-A1 5,6-Dialkyl-7-Amino-Azolopyrimidines, Method For Their Production, Their Use For Controlling Pathogenic Fungi and Agents Containing Said Compounds BASF AKTIENGESELLSCHAFT (DE) 2008-05-29 US disclosed
EP-1856120-A1 5,6-DIALKYL-7-AMINO-AZOLOPYRIMIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE FOR CONTROLLING PATHOGENIC FUNGI AND AGENTS CONTAINING SAID COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2007-11-21 EP disclosed
WO-2006092413-A1 5,6-DIALKYL-7-AMINO-AZOLOPYRIMIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE FOR CONTROLLING PATHOGENIC FUNGI AND AGENTS CONTAINING SAID COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-09-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080125445-A1 5,6-Dialkyl-7-Amino-Azolopyrimidines, Method For Their Production, Their Use For Controlling Pathogenic Fungi and Agents Containing Said Compounds AGPS, DERA, DPM1 KDM4E 1357/4885NPC1 3944/4885HPGD 2025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.