Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892909 | 1.00 | CHRM5 (0.70) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL5382728 | 0.90 | CHRM5 (0.62) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL5382725 | 0.90 | CHRM5 (0.62) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL16312050 | 0.87 | CHRM5 (0.58) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL14129051 | 0.83 | CHRM5 (0.54) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL24343471 | 0.83 | CHRM5 (0.62) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL1654602 | 0.82 | CHRM5 (1.00) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL10689028 | 0.82 | SMN1; SMN2 (0.65) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL7579153 | 0.82 | CHRM5 (0.60) | CHRM5TAAR1CYP1A2CYP3A4RECQL | |
| SCHEMBL10921731 | 0.82 | CHRM5 (0.60) | CHRM5TAAR1CYP1A2CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853352-B2 | Functionalized polymer and method for making | BRIDGESTONE CORPORATION (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20080154020-A1 | introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |