Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498035 | 1.00 | HRH3 (0.45) | HRH3KCNH2KDM1AHDAC6HDAC4 | |
| SCHEMBL2829438 | 1.00 | HRH3 (0.45) | HRH3KCNH2KDM1AHDAC6HDAC4 | |
| SCHEMBL1498101 | 1.00 | HRH3 (0.45) | HRH3KCNH2KDM1AHDAC6HDAC4 | |
| SCHEMBL1498079 | 1.00 | HRH3 (0.45) | HRH3KCNH2KDM1AHDAC6HDAC4 | |
| SCHEMBL1498075 | 0.85 | HRH3 (0.49) | HRH3KCNH2KDM1AHDAC4ALDH1A1 | |
| SCHEMBL16390950 | 0.84 | HRH3 (0.46) | HRH3KCNH2KDM1A | |
| SCHEMBL1498087 | 0.84 | HRH3 (0.46) | HRH3KCNH2KDM1A | |
| SCHEMBL1506311 | 0.83 | HRH3 (0.42) | HRH3KCNH2ALDH1A1 | |
| SCHEMBL1506313 | 0.83 | HRH3 (0.42) | HRH3KCNH2ALDH1A1 | |
| SCHEMBL1498048 | 0.81 | KDM1A (0.49) | HRH3KCNH2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242653-A1 | Cyclopropyl amine derivatives | ABBVIE INC. | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242653-A1 | Cyclopropyl amine derivatives | HRH3, HRH4, HRH2 | HRH3 1/4885KCNH2 949/4885KDM1A 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.