Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14026122 | 0.91 | CNR2 (0.57) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL4896771 | 0.89 | CNR2 (0.58) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL4895146 | 0.89 | CNR2 (0.58) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL4890277 | 0.89 | CNR2 (0.59) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| Formic Acid SCHEMBL4886208 | 0.88 | CNR2 (0.57) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL14026157 | 0.87 | CNR2 (0.51) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL4888826 | 0.87 | CNR2 (0.60) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| Formic Acid SCHEMBL4896490 | 0.84 | CNR2 (0.51) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL5708620 | 0.82 | CNR2 (0.55) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL4892375 | 0.80 | CNR2 (0.52) | CNR2CYP2C9CYP2C19CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261977-A1 | Pyrimidine Derivatives as Cannabinoid Receptor Modulators | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261977-A1 | Pyrimidine Derivatives as Cannabinoid Receptor Modulators | CNR2, CNR1, P2RY2 | CNR2 1/4885CYP2C9 729/4885CYP2C19 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.