Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274226 | 0.90 | SCN9A (0.45) | DPP4DPP8DPP7DPP9SCN9A | |
| SCHEMBL8274757 | 0.89 | DPP4 (0.44) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL4893295 | 0.89 | SCN9A (0.44) | DPP4DPP8DPP7DPP9SCN9A | |
| Hydrochloric Acid SCHEMBL4895076 | 0.89 | DPP4 (0.43) | DPP4DPP8DPP7DPP9SCN9A | |
| Hydrochloric Acid SCHEMBL4896192 | 0.88 | DPP4 (0.43) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL4899993 | 0.87 | DPP4 (0.40) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL4896879 | 0.86 | DPP4 (0.39) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4893398 | 0.86 | DPP4 (0.43) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL4896571 | 0.86 | DPP4 (0.42) | DPP4DPP8DPP7DPP9SCN9A | |
| Hydrochloric Acid SCHEMBL4886002 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP7DPP9SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009512-A1 | Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes | DPP4, DPP8, DPP3 | DPP4 1/4885DPP8 2/4885DPP7 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.